Research Experience

Mayo Clinic, Department of Quantitative Health Sciences Rochester, MN

Research Assistant, Advisor: Prof. Jun Chen March 2023 – March 2024

• Collaborated on the development of an R package for longitudinal microbiome and multi-omics data analysis, contributing over 12,000 lines of R code and authoring more than 10,000 words for the project's wiki. This package will be integrated into the MicrobiomeStat package.
• Created MicrobiomeGallery, a shiny platform for sharing advanced microbiome visualizations and code in an open-source, reproducible environment. Connect with fellow researchers, exchange knowledge, and contribute to the ever-growing microbiome community.

Case Western Reserve University, School of Medicine Cleveland, OH

Research Assistant, Advisor: Prof. Liangliang(Lyon) Zhang June 2022 – March 2023

• Processed 16S rRNA microbial community data using Qiime2, Galaxy, Phyloseq, and MicrobiomeAnalyst.

• Developed and implemented the ggpicrust2 R package, designed specifically for the analysis and visualization of PICRUSt2-predicted functional profiles in Metagenomics. This package has achieved over 5000 total downloads on both CRAN and Github and has been widely used by researchers in the field.

• Summarized the applications of statistical methods and machine learning techniques on microbiome research (writing a review for submission).

Southern Medical University & University of North Carolina at Chapel Hill, Institute for Global Health

Research Assistant, Advisor: Prof. Dong(Roman) Xu March 2021 – August 2022

• Assisted pediatricians in the development of standardized patient scenarios for evaluating the quality of basic medical care in China, specifically focused on pediatric diarrheal disease.

Skills

Technical Skills: R, Python, C, SAS, SPSS, Qiime2, Galaxy, MicrobiomeAnalyst

Education

Texas A&M University College Station, TX Ph.D. in Statistics, Advisors: Prof. Jun Chen and Prof. Xianyang Zhang August 2024 – May 2029 (Expected)

Southern Medical University Guangzhou, GD Bachelor of Science in Applied Statistics (Biostatistics) Sept. 2020 – June 2024 GPA: 3.95/4.00

Publications

Chen Yang, Jiahao Mai, Xuan Cao, Fabio Cominelli, Aaron Burberry, Liangliang(Lyon) Zhang (2023). ggpicrust2: an R package for PICRUSt2 predicted functional profile analysis and visualization. Bioinformatics. DOI: https://doi.org/10.1093/bioinformatics/btad470

Chen Yang, Jun Chen (2023). MicrobiomeStat: A Comprehensive R Package for Longitudinal Microbiome and Multi-Omics Data Analysis. Planned to submit to Bioinformatics.